Conolidine is really a pure alkaloid derived with the bark on the tropical shrub Tabernaemontana divaricata, also known as crepe jasmine. This shrub was traditionally Employed in Chinese, Ayurvedic, and Thai medication, and is well-known for its strong ache-relieving Qualities.Szpakowska et al. also studied conolidone and its action over the ACKR3